271 research outputs found

    Mitochondrial Dna Replacement Versus Nuclear Dna Persistence

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    In this paper we consider two populations whose generations are not overlapping and whose size is large. The number of males and females in both populations is constant. Any generation is replaced by a new one and any individual has two parents for what concerns nuclear DNA and a single one (the mother) for what concerns mtDNA. Moreover, at any generation some individuals migrate from the first population to the second. In a finite random time TT, the mtDNA of the second population is completely replaced by the mtDNA of the first. In the same time, the nuclear DNA is not completely replaced and a fraction FF of the ancient nuclear DNA persists. We compute both TT and FF. Since this study shows that complete replacement of mtDNA in a population is compatible with the persistence of a large fraction of nuclear DNA, it may have some relevance for the Out of Africa/Multiregional debate in Paleoanthropology

    Effect of migration in a diffusion model for template coexistence in protocells

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    The compartmentalization of distinct templates in protocells and the exchange of templates between them (migration) are key elements of a modern scenario for prebiotic evolution. Here we use the diffusion approximation of population genetics to study analytically the steady-state properties of such prebiotic scenario. The coexistence of distinct template types inside a protocell is achieved by a selective pressure at the protocell level (group selection) favoring protocells with a mixed template composition. In the degenerate case, where the templates have the same replication rate, we find that a vanishingly small migration rate suffices to eliminate the segregation effect of random drift and so to promote coexistence. In the non-degenerate case, a small migration rate greatly boosts coexistence as compared with the situation where there is no migration. However, increase of the migration rate beyond a critical value leads to the complete dominance of the more efficient template type (homogeneous regime). In this case, we find a continuous phase transition separating the homogeneous and the coexistence regimes, with the order parameter vanishing linearly with the distance to the transition point

    MARKOV DIFFUSIONS IN COMOVING COORDINATES AND STOCHASTIC QUANTIZATION OF THE FREE RELATIVISTIC SPINLESS PARTICLE

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    We revisit the classical approach of comoving coordinates in relativistic hydrodynamics and we give a constructive proof for their global existence under suitable conditions which is proper for stochastic quantization. We show that it is possible to assign stochastic kinematics for the free relativistic spinless particle as a Markov diffusion globally defined on M4{\sf M}^4. Then introducing dynamics by means of a stochastic variational principle with Einstein's action, we are lead to positive-energy solutions of Klein-Gordon equation. The procedure exhibits relativistic covariance properties.Comment: 31 pages + 1 figure available upon request; Plain REVTe

    The Settlement of Madagascar: What Dialects and Languages Can Tell Us

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    The dialects of Madagascar belong to the Greater Barito East group of the Austronesian family and it is widely accepted that the Island was colonized by Indonesian sailors after a maritime trek that probably took place around 650 CE. The language most closely related to Malagasy dialects is Maanyan, but Malay is also strongly related especially for navigation terms. Since the Maanyan Dayaks live along the Barito river in Kalimantan (Borneo) and they do not possess the necessary skill for long maritime navigation, they were probably brought as subordinates by Malay sailors. In a recent paper we compared 23 different Malagasy dialects in order to determine the time and the landing area of the first colonization. In this research we use new data and new methods to confirm that the landing took place on the south-east coast of the Island. Furthermore, we are able to state here that colonization probably consisted of a single founding event rather than multiple settlements.To reach our goal we find out the internal kinship relations among all the 23 Malagasy dialects and we also find out the relations of the 23 dialects to Malay and Maanyan. The method used is an automated version of the lexicostatistic approach. The data from Madagascar were collected by the author at the beginning of 2010 and consist of Swadesh lists of 200 items for 23 dialects covering all areas of the Island. The lists for Maanyan and Malay were obtained from a published dataset integrated with the author's interviews

    On the stochastic mechanics of the free relativistic particle

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    Given a positive energy solution of the Klein-Gordon equation, the motion of the free, spinless, relativistic particle is described in a fixed Lorentz frame by a Markov diffusion process with non-constant diffusion coefficient. Proper time is an increasing stochastic process and we derive a probabilistic generalization of the equation (dτ)2=−1c2dXνdXν(d\tau)^2=-\frac{1}{c^2}dX_{\nu}dX_{\nu}. A random time-change transformation provides the bridge between the tt and the τ\tau domain. In the τ\tau domain, we obtain an \M^4-valued Markov process with singular and constant diffusion coefficient. The square modulus of the Klein-Gordon solution is an invariant, non integrable density for this Markov process. It satisfies a relativistically covariant continuity equation

    Lexical evolution rates by automated stability measure

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    Phylogenetic trees can be reconstructed from the matrix which contains the distances between all pairs of languages in a family. Recently, we proposed a new method which uses normalized Levenshtein distances among words with same meaning and averages on all the items of a given list. Decisions about the number of items in the input lists for language comparison have been debated since the beginning of glottochronology. The point is that words associated to some of the meanings have a rapid lexical evolution. Therefore, a large vocabulary comparison is only apparently more accurate then a smaller one since many of the words do not carry any useful information. In principle, one should find the optimal length of the input lists studying the stability of the different items. In this paper we tackle the problem with an automated methodology only based on our normalized Levenshtein distance. With this approach, the program of an automated reconstruction of languages relationships is completed

    2d frustrated Ising model with four phases

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    In this paper we consider a 2d random Ising system on a square lattice with nearest neighbour interactions. The disorder is short range correlated and asymmetry between the vertical and the horizontal direction is admitted. More precisely, the vertical bonds are supposed to be non random while the horizontal bonds alternate: one row of all non random horizontal bonds is followed by one row where they are independent dichotomic random variables. We solve the model using an approximate approach that replace the quenched average with an annealed average under the constraint that the number of frustrated plaquettes is keep fixed and equals that of the true system. The surprising fact is that for some choices of the parameters of the model there are three second order phase transitions separating four different phases: antiferromagnetic, glassy-like, ferromagnetic and paramagnetic.Comment: 17 pages, Plain TeX, uses Harvmac.tex, 4 ps figures, submitted to Physical Review

    The Slippery Slope of MIS Academia: A Discussion of the Quest for Relevance in Our Discipline

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    The MIS discipline faces the need to periodically re-establish its relevance to both academics and practitioners. Evolving technology forces our discipline to change at a rate far exceeding that of other business disciplines. In the workplace, rapidly evolving IT management issues and technologies have led corporations to manage technical employees differently than other employees. In academia, however, MIS faculty are faced with the same expectations as other business faculty. The current model of MIS as an academic discipline has many issues that make staying current and relevant very difficult. The result is that MIS research and teaching lag practice. One might argue that as the field matures, we are falling further behind. This paper is the outcome of a panel discussion held during the 2006 Americas Conference on Information Systems in Acapulco, Mexico. The panel discussed the assertions that MIS is on a Slippery Slope that threatens our existence as a business discipline and that our current model encourages irrelevance, both in research and in teaching. Panel members were asked to share their views on five questions relative to the Slippery Slope from their unique perspectives

    Evolution of the most recent common ancestor of a population with no selection

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    We consider the evolution of a population of fixed size with no selection. The number of generations GG to reach the first common ancestor evolves in time. This evolution can be described by a simple Markov process which allows one to calculate several characteristics of the time dependence of GG. We also study how GG is correlated to the genetic diversity.Comment: 21 pages, 10 figures, uses RevTex4 and feynmf.sty Corrections : introduction and conclusion rewritten, references adde

    Genetic Polymorphism in Evolving Population

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    We present a model for evolving population which maintains genetic polymorphism. By introducing random mutation in the model population at a constant rate, we observe that the population does not become extinct but survives, keeping diversity in the gene pool under abrupt environmental changes. The model provides reasonable estimates for the proportions of polymorphic and heterozygous loci and for the mutation rate, as observed in nature
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